Leaky Gut Syndome

The Link Between Leaky Gut Syndrome And Depression

Another study published in 2008 showed that among people who were diagnosed with major depression, clinical indicators for leaky gut syndrome were “significantly greater.” The study concluded that people with major depression should be “checked for leaky gut” via a test for immune system antibodies, and treated accordingly.

New Understanding Of The Link Between Leaky Gut Syndrome And Autoimmune Disorders

An article published in February of 2012 discusses how a certain protein called “zonulin” has been identified as key actor in the functioning of the “tight junctions” that hold the cells together that comprise the wall of the intestine. When zonulin is “deregulated in genetically susceptible individuals, autoimmune disorders can occur.”

When the function of zonulin is “normalized” the tight junctions begin to function in a more proper way. Researchers are still trying to figure out exactly what causes zonulin to “go haywire” but there is general agreement that the protocols to combat leaky gut do help.

Article Conclusion

We reference these studies at the end of this article to show people that there is a great deal of research being done in this area. Because this is a relatively new area of focus for the medical community, there is skepticism and confusion. But a consensus is starting to come into focus about how to identify and treat leaky gut syndrome.

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• References

  Derrien M, et al. Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. IJSEM 2004 Sept; 54(5): 1469-76.

  dos Santos RG, et al. Glutamine supplementation decreases intestinal permeability and preserves gut mucosa integrity in an experimental mouse model.

  JPEN J Parenter Enteral Nutr. 2010 Jul-Aug;34(4):408-13.

  Foley S, et al. Characterisation of glutamine fructose-6-phosphate amidotransferase (EC 2.6.1.16) and N-acetylglucosamine metabolism in Bifidobacterium. Arch Microbiol. 2008 Feb;189(2):157-67.

  Grzanna R, et al. Ginger — an herbal medicinal product with broad anti-inflammatory actions. J Med Food. 2005 Summer;8(2):125-32.

  Resta-Lenert S, et al. Probiotics and commensals reverse TNF-alpha- and IFN-gamma-induced dysfunction in human intestinal epithelial cells. Gastroenterology. 2006 Mar;130(3):731-46.

  Rosenfeldt V, et al. Effect of probiotics on gastrointestinal symptoms and small intestinal permeability in children with atopic dermatitis. J Pediatr. 2004 Nov;145(5):612-6.

  Shen L, et al. Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed. Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G577-82.

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